Fass J, Silny J, Braun J, Heindrichs U, Dreuw B, Schumpelick V, Rau G
Dept. of Surgery, Rheinisch Westphälische Technische Hochschule, Aachen, Germany.
Scand J Gastroenterol. 1994 Aug;29(8):693-702. doi: 10.3109/00365529409092496.
The study was undertaken to determine the validity of intraluminal impedance measuring for the diagnosis of esophageal motility disorders in reflux patients.
A new impedance device was used for the detection of esophageal motility patterns in a prospective study with 10 volunteers and 10 patients with reflux esophagitis grade II-III. Perfused manometry was correlated with the impedance tracings. Test meals were saline and curd in three different preparations with liquid to semisolid viscosity.
There was a marked delay in esophageal transport with increasing viscosity of the bolus (p < 0.01). A significant (p < 0.001) delay of the bolus transport in the inflamed esophageal areas was seen in reflux patients. A reduced contractility of the lower esophagus and the lower esophageal sphincter was detected by the impedance procedure in reflux patients, indicating that the pathologic motility patterns in reflux esophagitis are most likely secondary to the tissue inflammation.
We conclude that impedance procedures may give additional significant information about bolus transport and esophageal wall movements.
本研究旨在确定腔内阻抗测量法对反流患者食管动力障碍诊断的有效性。
在一项前瞻性研究中，使用一种新的阻抗装置检测10名志愿者和10名患有II - III级反流性食管炎患者的食管动力模式。将灌注测压法与阻抗描记图进行关联。测试餐为三种不同制剂的生理盐水和凝乳，其粘度从液体到半固体。
随着食团粘度增加，食管运输明显延迟（p < 0.01）。在反流患者中，可见炎症食管区域食团运输显著延迟（p < 0.001）。通过阻抗检测程序发现反流患者食管下段和食管下括约肌收缩力降低，这表明反流性食管炎的病理动力模式很可能继发于组织炎症。
我们得出结论，阻抗检测程序可能会提供有关食团运输和食管壁运动的其他重要信息。
