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乌头碱中毒:全球视角

Aconitine poisoning: a global perspective.

作者信息

Chan T Y

机构信息

Department of Clinical Pharmacology, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories.

出版信息

Vet Hum Toxicol. 1994 Aug;36(4):326-8.

PMID:7975141
Abstract

The circumstances under which poisoning by the Aconitum species or their derivatives occurred since 1950s are reviewed. Aconitine poisoning is far more common in Asia, particularly China and Hong Kong, than in the western countries. This may be because of the widespread use of herbal medicines by the Asian communities. Outside Asia, poisoning usually occurs after ingesting the wild plant of the Aconitum species. Asians may still have easy access to herbal medicines even when living in western countries.

摘要

回顾了自20世纪50年代以来乌头属植物及其衍生物中毒的发生情况。乌头碱中毒在亚洲,尤其是中国和中国香港,比在西方国家更为常见。这可能是因为亚洲人群广泛使用草药。在亚洲以外地区,中毒通常发生在摄入乌头属野生植物之后。亚洲人即使生活在西方国家,可能仍然容易获得草药。

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Aconitine poisoning: a global perspective.乌头碱中毒:全球视角
Vet Hum Toxicol. 1994 Aug;36(4):326-8.
2
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The spectrum of poisonings in Hong Kong: an overview.香港中毒情况概述
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2
Identification of key transporters mediating uptake of aconitum alkaloids into the liver and kidneys and the potential mechanism of detoxification by active ingredients of liquorice.介导乌头生物碱摄取进入肝脏和肾脏的关键转运体的鉴定以及甘草活性成分的潜在解毒机制。
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Aconitine induces cardiomyocyte damage by mitigating BNIP3-dependent mitophagy and the TNFα-NLRP3 signalling axis.乌头碱通过减轻 BNIP3 依赖性自噬和 TNFα-NLRP3 信号轴诱导心肌细胞损伤。
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