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腹腔镜与开腹阑尾切除术治疗疑似阑尾炎的前瞻性研究

Laparoscopic versus open appendicectomy for suspected appendicitis: a prospective study.

作者信息

Kollias J, Harries R H, Otto G, Hamilton D W, Cox J S, Gallery R M

机构信息

Department of Surgery, Modbury Hospital, Adelaide, Australia.

出版信息

Aust N Z J Surg. 1994 Dec;64(12):830-5. doi: 10.1111/j.1445-2197.1994.tb04558.x.

Abstract

Despite recent advances in minimally invasive surgery, laparoscopic appendicectomy has been questioned as a feasible method of treating patients with suspected appendicitis because open appendicectomy carries few risks and complications. Between February 1992 and January 1993 a non-randomized prospective study comparing open and laparoscopic appendicectomy was designed to assess differences in postoperative morbidity, pain, inpatient hospital stay and a return to normal lifestyle. One hundred and sixty-seven patients with suspected clinical appendicitis were assigned to open (n = 74) or laparoscopic (n = 93) appendicectomy. Six patients were excluded due to the presence of other significant pathology such that the appendix was not removed. Eighty-seven patients underwent attempted laparoscopic appendicectomy, of which 81 were completed. The diagnosis of appendicitis was confirmed histologically in 63.5% of patients undergoing open appendicectomy and 63% of patients undergoing laparoscopic appendicectomy. There were no significant differences in anaesthetic times, postoperative morbidity and analgesic requirements. There was a significant reduction in both postoperative inpatient stay (P < 0.0001) and time taken to return to work or normal activities (P < 0.0001) for the laparoscopic group. The use of laparoscopy for patients with suspected appendicitis aids definitive diagnosis and should reduce the negative appendicectomy rate to an acceptable figure. The results suggest that laparoscopic appendicectomy is safe and offers advantages over open appendicectomy in the management of patients with suspected appendicitis.

摘要

尽管近年来微创手术取得了进展,但腹腔镜阑尾切除术作为治疗疑似阑尾炎患者的一种可行方法受到了质疑,因为开放性阑尾切除术的风险和并发症较少。1992年2月至1993年1月,设计了一项比较开放性和腹腔镜阑尾切除术的非随机前瞻性研究,以评估术后发病率、疼痛、住院时间和恢复正常生活方式方面的差异。167例疑似临床阑尾炎患者被分配接受开放性(n = 74)或腹腔镜(n = 93)阑尾切除术。6例患者因存在其他严重病变而未切除阑尾,故被排除。87例患者尝试进行腹腔镜阑尾切除术,其中81例完成。接受开放性阑尾切除术的患者中63.5%和接受腹腔镜阑尾切除术的患者中63%经组织学证实为阑尾炎。麻醉时间、术后发病率和镇痛需求方面无显著差异。腹腔镜组术后住院时间(P < 0.0001)和恢复工作或正常活动所需时间(P < 0.0001)均显著缩短。对疑似阑尾炎患者使用腹腔镜有助于明确诊断,并应将阴性阑尾切除术率降低到可接受的水平。结果表明,腹腔镜阑尾切除术是安全的,在疑似阑尾炎患者的治疗中比开放性阑尾切除术更具优势。

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