Drut R, Quijano G, Jones M C, Scanferla P
Servicio de Patología, Hospital Superiora Sor María Ludovica, La Plata.
Medicina (B Aires). 1994;54(1):1-5.
We are reporting the necropsy findings of 7 patients poisoned with diethylene glycol-contaminated propolis (a rubbery substance produced by bees from vegetal resins). Besides the well-known features of hydropic necrosis of centrolobular areas in the liver and renal tubules we found acute pancreatitis with diffuse enzymatic fat necrosis which in two of the cases was considered the secondary cause of death, and acute demyelinating lesions in the central and peripheral nervous system. Six out of the 7 cases showed glomerular PAS-positive arteriolar hyalinosis at the vascular pole, in two of them widely disseminated. Differing from the findings reported in ethylene glycol poisoning we could not find calcium oxalate crystals in any of the cases. The pancreatic, central and peripheral nervous system lesions as well as the glomerular arteriolar hyalinosis have not been previously described in the literature in relation with diethylene glycol poisoning.
我们报告了7例因受二甘醇污染的蜂胶（蜜蜂从植物树脂中产生的一种橡胶状物质）中毒患者的尸检结果。除了众所周知的肝小叶中心区和肾小管水样坏死特征外，我们还发现了急性胰腺炎伴弥漫性酶性脂肪坏死，其中2例被认为是次要死因，以及中枢和周围神经系统的急性脱髓鞘病变。7例中有6例在血管极处显示肾小球PAS阳性小动脉玻璃样变，其中2例广泛分布。与乙二醇中毒报告的结果不同，我们在任何病例中均未发现草酸钙晶体。胰腺、中枢和周围神经系统病变以及肾小球小动脉玻璃样变此前在文献中尚未与二甘醇中毒相关联地描述过。
