Bell M D, Lysaker P H, Beam-Goulet J L, Milstein R M, Lindenmayer J P
VA Medical Center, West Haven, CT 06516.
Psychiatry Res. 1994 Jun;52(3):295-303. doi: 10.1016/0165-1781(94)90075-2.
A five-component model of schizophrenia has been presented by Kay and Sevy based upon an analysis of the Positive and Negative Syndrome Scale. Kay and Sevy found factorial validity for negative and positive syndromes, and they identified excitement, depressive, and cognitive components as well. They suggested that subtypes and syndromes can be mapped along dimensions presented in their model. The present study compares the five-component solution for a new sample of 146 subjects to a reanalysis of the Kay and Sevy data. Despite divergent demographic characteristics, the two samples produce similar dimensions. Correlations of component loadings and subject scores as well as confirmatory factor analysis are presented. Discussion focuses on points of agreement and important differences in the symptoms assigned to each component. How the dimensions relate to rationally derived models of positive and negative syndromes is reviewed, and implications for subtyping and other methods of examining the heterogeneity of schizophrenia are considered.
凯和塞维基于对阳性和阴性症状量表的分析，提出了精神分裂症的五成分模型。凯和塞维发现阴性和阳性症状具有因子效度，并且他们还识别出了兴奋、抑郁和认知成分。他们认为亚型和综合征可以沿着其模型中呈现的维度进行映射。本研究将146名受试者的新样本的五成分解决方案与对凯和塞维数据的重新分析进行了比较。尽管人口统计学特征不同，但两个样本产生了相似的维度。文中呈现了成分载荷与受试者分数的相关性以及验证性因素分析。讨论聚焦于各成分所分配症状的一致点和重要差异。回顾了这些维度与基于理性推导的阳性和阴性综合征模型的关系，并考虑了其对亚型划分及其他检查精神分裂症异质性方法的意义。
