Nikawa H, Yamamoto T, Hayashi S, Nikawa Y, Hamada T
Department of Prosthetic Dentistry, Hiroshima University School of Dentistry, Japan.
J Oral Rehabil. 1994 Sep;21(5):585-94. doi: 10.1111/j.1365-2842.1994.tb01173.x.
Effects of soft lining materials on the growth and/or acid production of Candida albicans were investigated using a simplified method monitoring the pH change in the growth medium. Reverse sigmoidal pH curves were observed with all samples and, as compared with acrylic, all soft lining materials inhibited fungal growth or acid production in the following way, i.e. delay of the beginning of a rapid and linear decline in pH, decreases in the rate of linear change in pH and increases in minimum pH. Further examinations using a surface-modified glass tube revealed that the order of Candida growth agreed with the relative hydrophobicity and adherence capacity of substrates, suggesting that this adherence capacity affected the yeast growth on their surfaces. Besides adherence capacities of substrates, the powder, liquid and plasticizer of some soft lining materials directly inhibited Candida growth. Thus, the results obtained here revealed that several factors within soft lining materials affected Candida growth and/or acid production.
采用一种监测生长培养基pH变化的简化方法，研究了软衬材料对白色念珠菌生长和/或产酸的影响。所有样品均观察到反向S形pH曲线，与丙烯酸树脂相比，所有软衬材料均以以下方式抑制真菌生长或产酸，即延迟pH快速线性下降的开始，降低pH线性变化速率，并提高最低pH值。使用表面改性玻璃管进行的进一步研究表明，念珠菌生长顺序与底物的相对疏水性和粘附能力一致，这表明这种粘附能力影响酵母在其表面的生长。除了底物的粘附能力外，一些软衬材料的粉末、液体和增塑剂直接抑制念珠菌生长。因此，此处获得的结果表明，软衬材料中的几个因素会影响念珠菌的生长和/或产酸。
