Waters M G, Williams D W, Jagger R G, Lewis M A
Dental School, University of Wales College of Medicine, Cardiff, United Kingdom.
J Prosthet Dent. 1997 Mar;77(3):306-12. doi: 10.1016/s0022-3913(97)70188-4.
Colonization of denture soft lining materials by Candida albicans can result in clinical problems. Two experimental silicone soft lining materials have been developed and demonstrate good physical properties.
The aim of this study was to determine the extent of candidal adherence to these materials compared with a commercially available soft lining material and an acrylic resin denture base.
The experimental materials were constructed in a stainless-steel mold, and their surface energies were determined with a dynamic contact angle analyzer. The adherence of three strains of C. albicans was determined with an in vitro assay. In addition, one test strain was used to determine the effect on adherence of precoating the materials with whole saliva.
Adhesion to all materials was strain variable, with the lowest adherence recorded for the two experimental materials. Decreased adherence was also apparent after precoating the materials with saliva. Correlation between surface energy of the material and the degree of candidal adhesion was seen for one strain, but no correlation was seen for the other two strains.
Adherence of C. albicans to the two experimental silicone soft lining materials was significantly less than that for an acrylic resin denture base and a commercially available soft lining material.
白色念珠菌在义齿软衬材料上的定植可导致临床问题。已研发出两种实验性硅酮软衬材料，它们具有良好的物理性能。
本研究的目的是确定与市售软衬材料和丙烯酸树脂义齿基托相比，念珠菌对这些材料的黏附程度。
实验材料在不锈钢模具中制作而成，其表面能通过动态接触角分析仪测定。采用体外试验测定三株白色念珠菌的黏附情况。此外，使用一株测试菌株来确定用全唾液预涂覆材料对黏附的影响。
对所有材料的黏附情况因菌株而异，两种实验材料的黏附率最低。用唾液预涂覆材料后，黏附率也明显降低。对于一株菌株，观察到材料表面能与念珠菌黏附程度之间存在相关性，但对于另外两株菌株则未观察到相关性。
白色念珠菌对两种实验性硅酮软衬材料的黏附明显少于对丙烯酸树脂义齿基托和市售软衬材料的黏附。
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