van der Hul R, Plaisier P, Jeekel J, Terpstra O, den Toom R, Bruining H
Department of Surgery, University Hospital Rotterdam, Netherlands.
Endoscopy. 1994 Sep;26(7):573-8. doi: 10.1055/s-2007-1009042.
To study the efficacy of extracorporeal shock-wave lithotripsy (ESWL) of pancreatic duct stones, seventeen patients (mean age: 42 years) with recurrent attacks of abdominal pain as a result of chronic calcifying pancreatitis were treated with this method. In all cases, endoscopic removal of the stones proved impossible. When there was fragmentation, the remaining calculi and fragments either evacuated spontaneously, or attempts were made to extract them endoscopically, followed by flushing. In 13 patients (76%), fragmentation of stones was achieved, and 11 of these patients had dramatic pain relief directly after ESWL (65%). However, complete ductal clearance of stones was achieved in only seven patients (41%); at the last follow-up (12-59 months after ESWL, mean: 30 months), all seven were free of symptoms. Of the six patients with stone fragmentation without ductal clearance, three were operated on because of recurrent complaints. The only complication due to the procedure was an exacerbation of pancreatitis in one patient, which was treated conservatively. If pancreatic stones cannot be removed endoscopically, ESWL seems to be preferable to surgery, which may still be performed in case of failure. It seems important to achieve ductal clearance and not merely stone disintegration in order to obtain the desired long-term clinical effects.
为研究体外冲击波碎石术(ESWL)治疗胰管结石的疗效,我们采用该方法治疗了17例因慢性钙化性胰腺炎反复发作腹痛的患者(平均年龄:42岁)。在所有病例中,经内镜取石均未成功。结石碎裂后,残留结石及碎片要么自行排出,要么尝试经内镜取出,随后进行冲洗。13例患者(76%)实现了结石碎裂,其中11例患者在ESWL后疼痛立即显著缓解(65%)。然而,仅7例患者(41%)实现了结石完全清除;在最后一次随访(ESWL后12 - 59个月,平均30个月)时,所有7例患者均无症状。6例结石碎裂但未实现导管清除的患者中,3例因反复出现症状而接受了手术。该手术唯一的并发症是1例患者胰腺炎加重,经保守治疗。如果胰管结石无法经内镜取出,ESWL似乎比手术更可取,手术可在失败时进行。为获得理想的长期临床效果,实现导管清除而非仅仅使结石碎裂似乎很重要。