Solovenchuk L L, Pereverzeva V V, Nevretdinova Z G
Genetika. 1994 Sep;30(9):1260-7.
Peculiarities of the frequency distribution of antigens and haplotypes of A, B, and Cw subloci of the HLA system in 924 Slavic inhabitants of Magadan are described. Significant differences in gene and haplotype frequencies between inhabitants of Magadan and those of Moscow, Odessa, Poles'e, Latvia, and England were revealed, which could not be attributed solely to the specificity of migration processes. On the basis of an analysis of gamete associations of the A and B subloci, an attempt was made to explain the specificity of the frequency distribution of HLA system alleles and haplotypes in the investigated sample from an ecological point of view.
描述了马加丹924名斯拉夫居民中HLA系统A、B和Cw亚位点抗原及单倍型的频率分布特点。揭示了马加丹居民与莫斯科、敖德萨、波列西耶、拉脱维亚和英国居民在基因和单倍型频率上存在显著差异，这些差异不能仅归因于迁移过程的特殊性。基于对A和B亚位点配子关联的分析，试图从生态学角度解释所研究样本中HLA系统等位基因和单倍型频率分布的特殊性。
