Herrinton L J, Weiss N S, Koepsell T D, Daling J R, Taylor J W, Lyon J L, Swanson G M, Greenberg R S
Department of Epidemiology, University of Washington, Seattle.
Am J Public Health. 1994 Jul;84(7):1142-4. doi: 10.2105/ajph.84.7.1142.
An interview study of persons diagnosed with multiple myeloma between 1977 and 1981 and suitable control subjects was conducted to test the hypothesis that exposure to hair dyes increases the risk of multiple myeloma. Among women, there was little evidence that prior regular use of hair dyes (odds ratio [OR] = 1.0; 95% confidence interval [CI] = 0.70, 1.4) or prior employment as a hairdresser (OR = 1.1; 95% CI = 0.43, 2.7) increased risk; however, the former comparison was limited by the lack of detailed information concerning the exposure. Among men, there was a modest association of regular use of hair dyes (OR = 1.5; 95% CI = 0.75, 2.9) with myeloma, but this was based on a small number of exposed persons.
开展了一项针对1977年至1981年间被诊断为多发性骨髓瘤的患者以及合适的对照对象的访谈研究，以检验接触染发剂会增加患多发性骨髓瘤风险这一假设。在女性中，几乎没有证据表明既往经常使用染发剂（优势比[OR]=1.0；95%置信区间[CI]=0.70，1.4）或既往从事美发师工作（OR=1.1；95%CI=0.43，2.7）会增加患病风险；然而，前一项比较因缺乏有关接触情况的详细信息而受到限制。在男性中，经常使用染发剂与骨髓瘤之间存在适度关联（OR=1.5；95%CI=0.75，2.9），但这是基于少量接触者得出的。
