Teta M J, Walrath J, Meigs J W, Flannery J T
J Natl Cancer Inst. 1984 May;72(5):1051-7.
This cohort study examined cancer incidence in 13,650 Connecticut cosmetologists who had held licenses for 5 years or more and had begun hairdressing school prior to January 1, 1966. Cancer incidence rates for the general Connecticut population, 1935-78, were compared with those for 11,845 female and 1,805 male cosmetologists. The females had a standardized cancer incidence ratio (SIR) of 112 (P less than .01). A significant excess of lung cancer (SIR = 141) and excesses of brain (SIR = 168) and ovarian cancer (SIR = 134) of borderline significance were observed. No significant cancer risk was evident for female cosmetologists licensed since 1935, even for those with 35 years or more of follow-up, although the SIRs for brain cancer, lymphoma, and leukemia were elevated. Female cosmetologists who entered the profession between 1925 and 1934, however, experienced a significant overall cancer incidence (SIR = 129) and significant excesses of respiratory, breast, corpus uterine, and ovarian cancers. Those with 35 years or more from time of first license appeared to be at the highest risk. Among males the overall cancer incidence rate was close to that expected (SIR = 105). Smoking habits and reproductive factors that could not be taken into account may explain some of the excesses among females. Although no specific occupational agent could be identified, the excess numbers of leukemias in females and brain cancers among males and females merit continued surveillance.
这项队列研究调查了13650名康涅狄格州的美容师的癌症发病率,这些美容师持有执照5年或更长时间,并且在1966年1月1日前开始就读美发学校。将1935 - 1978年康涅狄格州普通人群的癌症发病率与11845名女性和1805名男性美容师的发病率进行了比较。女性的标准化癌症发病率比(SIR)为112(P小于0.01)。观察到肺癌显著过量(SIR = 141)以及脑癌(SIR = 168)和卵巢癌(SIR = 134)有接近显著水平的过量。自1935年起获得执照的女性美容师,即使有35年或更长时间的随访,也未发现明显的癌症风险,尽管脑癌、淋巴瘤和白血病的SIR有所升高。然而,在1925年至1934年间进入该行业的女性美容师,总体癌症发病率显著(SIR = 129),呼吸系统、乳腺癌、子宫体癌和卵巢癌显著过量。从首次获得执照起有35年或更长时间的人似乎风险最高。男性的总体癌症发病率接近预期(SIR = 105)。无法考虑的吸烟习惯和生殖因素可能解释了女性中的一些过量情况。尽管无法确定具体的职业因素,但女性白血病以及男性和女性脑癌的过量病例值得持续监测。