来自海绵动物洞穴棘海绵的六种新的二萜异腈类化合物。

Six new diterpene isonitriles from the sponge Acanthella cavernosa.

作者信息

Trimurtulu G, Faulkner D J

机构信息

Scripps Institution of Oceanography, University of California, San Diego, La Jolla 92093-0212.

出版信息

J Nat Prod. 1994 Apr;57(4):501-6. doi: 10.1021/np50106a009.

DOI:10.1021/np50106a009

PMID:8021650

Abstract

Six new diterpene isonitriles, 10-epi-isokalihinol F [1], 10-epi-isokalihinol H [2], 1-epi-kalihinene [4], 15-isothiocyanato-1-epi-kalihinene [5], 1,10-diepi-kalihinene [6], and kalihipyran [7] were isolated, together with the known compound isokalihinol B [3], from Acanthella cavernosa collected in the Seychelles. The structures of the new diterpenes were elucidated by interpretation of spectral data. The ring system of kalihipyran [7] differs from that of the kalihinols and kalihinenes.

摘要

从塞舌尔采集的海绵状棘海绵（Acanthella cavernosa）中分离出6种新的二萜异腈类化合物，10-表异卡利希醇F [1]、10-表异卡利希醇H [2]、1-表卡利希烯[4]、15-异硫氰酸酯-1-表卡利希烯[5]、1,10-二表卡利希烯[6]和卡利希吡喃[7]，以及已知化合物异卡利希醇B [3]。通过光谱数据解析阐明了新二萜的结构。卡利希吡喃[7]的环系与卡利希醇和卡利希烯的不同。