Fujio N, Feke G T, Goger D G, McMeel J W
Schepens Eye Research Institute, Boston, MA 02114.
Br J Ophthalmol. 1994 May;78(5):335-8. doi: 10.1136/bjo.78.5.335.
Regional changes in retinal blood flow following inferior and subsequent superior argon laser half fundus photocoagulation treatment were measured in six diabetic patients with advanced retinopathy. Centreline blood velocity, vessel diameter, and blood flow in major inferior and superior temporal retinal arteries were measured at baseline and following each treatment using the bidirectional laser Doppler technique and monochromatic fundus photography. Inferior fundus laser treatment produced a significant blood flow decrease in inferior temporal arteries ranging from 60% to 78%. Blood flow changes in superior temporal arteries were not significant, ranging from -7% to +14%. Subsequent superior fundus laser treatment produced a significant blood flow decrease in superior temporal arteries ranging from 50% to 66%. Subsequent blood flow changes in inferior temporal arteries were not significant, ranging from -19% to +21%. The results indicate that regional laser treatment produces a regional reduction in retinal blood flow, consistent with measurements of preretinal and intraretinal oxygen tension which have indicated increases in oxygen over photocoagulated regions.
对6例患有晚期视网膜病变的糖尿病患者，测量了氩激光下半部及随后上半部眼底光凝治疗后视网膜血流的区域变化。使用双向激光多普勒技术和单色眼底摄影，在基线时以及每次治疗后测量主要颞下和颞上视网膜动脉的中心线血流速度、血管直径和血流量。下半部眼底激光治疗使颞下动脉血流量显著降低，降幅在60%至78%之间。颞上动脉的血流变化不显著，在-7%至+14%之间。随后的上半部眼底激光治疗使颞上动脉血流量显著降低，降幅在50%至66%之间。随后颞下动脉的血流变化不显著，在-19%至+21%之间。结果表明，局部激光治疗会使视网膜血流出现局部减少，这与视网膜前和视网膜内氧张力的测量结果一致，后者表明光凝区域的氧含量增加。
