Macleod I C, Irvine D S, Masterton A, Taylor A, Templeton A A
Department of Obstetrics and Gynaecology, University of Aberdeen, Aberdeen Maternity Hospital, Foresterhill, UK.
Hum Reprod. 1994 Feb;9(2):310-9. doi: 10.1093/oxfordjournals.humrep.a138499.
A comparative assessment of the conventional criteria of semen quality (sperm concentration, motility and morphology) was undertaken by standard laboratory techniques and by means of a computer-assisted image analysis system (the Hamilton-Thorn HTM-S 2030) in an open prospective study, in the context of a service andrology laboratory. A total of 1435 semen samples submitted by couples in the course of routine infertility investigations were examined by both methods, and the results compared. It was observed that the method did not provide comparable data on semen quality, either in respect of sperm concentration or graded motility, while the morphometric data generated by the HTM-S did not appear to be related to conventional morphology assessment. The clinical value of such systems in the assessment of the classical determinants of semen quality requires formal assessment in properly conducted large scale prospective studies.
在一家男科服务实验室开展的一项开放性前瞻性研究中，运用标准实验室技术并借助计算机辅助图像分析系统（汉密尔顿-桑恩HTM-S 2030），对精液质量的传统标准（精子浓度、活力和形态）进行了比较评估。两种方法对1435份在常规不孕症检查过程中由夫妇提交的精液样本进行了检测，并对结果进行了比较。结果发现，该方法在精子浓度或分级活力方面均未提供关于精液质量的可比数据，而HTM-S生成的形态计量学数据似乎与传统形态学评估无关。此类系统在评估精液质量经典决定因素方面的临床价值需要在适当开展的大规模前瞻性研究中进行正式评估。
