Obafunwa J O, Busuttil A
Department of Pathology, University Medical School, Edinburgh, UK.
Postgrad Med J. 1994 Jun;70(824):428-32. doi: 10.1136/pgmj.70.824.428.
Of the 400 consecutive completed suicides investigated over a 5-year period, 114 (28.5%) who had consulted a doctor in the week preceding death were specifically reviewed and compared with those who did not. The study comprised an analysis of the medical history, the scene of death and a complete autopsy with histological and toxicological examination and the identification of features which occurred more frequently in this group when compared with other suicides not contacting their doctors. Suicide-associated factors include psychiatric illness (58.8%), deteriorating health (16.7%), and a loss of spouse (7.0%); all these features were manifested by this group of suicides more frequently than by those who made no clinical contact (P < 0.001). A pre-indication of suicidal intention was made by 45% of these patients. This feature, as with previous attempts, occurred more commonly in patients who consulted a doctor (P < 0.001). Drug overdose was the most common suicidal method chosen (50.9%) and anti-depressants predominated (35%); 78% of those who overdosed ingested prescribed drugs. Poisoning was more common in this group (P < 0.001). Half of the victims committed suicide within 24 hours following consultation; of these, 51% overdosed on drugs with 61% of them ingesting their prescribed drugs. Of these 114 cases, the final consultation in 43% was to collect more drugs. All suicidal threats should be taken seriously, and particular care should be taken in prescribing and dispensing medication which may be fatal in overdose.
在一项为期5年的调查中,对400例连续完成的自杀案例进行了研究,其中114例(28.5%)在死亡前一周内咨询过医生,对这部分案例进行了专门审查,并与未咨询过医生的案例进行了比较。该研究包括对病史、死亡现场的分析,以及完整的尸检,包括组织学和毒理学检查,并确定与未联系医生的其他自杀案例相比,该组中更频繁出现的特征。与自杀相关的因素包括精神疾病(58.8%)、健康状况恶化(16.7%)和配偶死亡(7.0%);所有这些特征在这组自杀案例中的表现都比未进行临床接触的案例更为频繁(P<0.001)。45%的患者有自杀意图的预先迹象。与之前的自杀未遂情况一样,这一特征在咨询过医生的患者中更为常见(P<0.001)。药物过量是最常见的自杀方式(50.9%),其中抗抑郁药占主导(35%);78%过量服药者服用的是处方药。中毒在该组中更为常见(P<0.001)。一半的受害者在咨询后的24小时内自杀;其中,51%过量服药,61%服用的是处方药。在这114例案例中,43%的最后一次咨询是为了获取更多药物。所有自杀威胁都应予以重视,在开处方和配药时应特别小心,因为过量服用可能致命。