Darke S, Hall W, Swift W
National Drug and Alcohol Research Centre, University of New South Wales, Kensington, Australia.
Drug Alcohol Depend. 1994 Feb;34(3):253-7. doi: 10.1016/0376-8716(94)90164-3.
A sample of 222 methadone maintenance (MM) clients were tested for a diagnosis of antisocial personality disorder (ASPD). The majority (60.8%) of clients qualified for a lifetime diagnosis of ASPD, 25.7% received a current diagnosis of ASPD, and a conduct disorder of childhood was diagnosed for 68.5% of subjects. The most common symptoms of ASPD among MM clients were unlawful behaviours, aggressiveness and recklessness. Lack of remorse was reported by less than a third of subjects with a lifetime diagnosis of ASPD. Subjects with a current diagnosis of ASPD had been retained in treatment as long as other clients, and were no more likely to be currently injecting or sharing injecting equipment. It is concluded that clients with ASPD can be retained in MM treatment, and can respond to MM treatment as well as other clients.
对222名美沙酮维持治疗（MM）患者进行了检测，以诊断其是否患有反社会人格障碍（ASPD）。大多数（60.8%）患者符合ASPD终身诊断标准，25.7%被诊断为当前患有ASPD，68.5%的受试者被诊断为童年期品行障碍。MM患者中ASPD最常见的症状是非法行为、攻击性和鲁莽。在终身诊断为ASPD的受试者中，不到三分之一的人报告缺乏悔恨感。当前被诊断为ASPD的受试者在治疗中的留存时间与其他患者相同，且目前注射或共用注射设备的可能性并不更高。研究得出结论，患有ASPD的患者可以留在MM治疗中，并且对MM治疗的反应与其他患者一样。
