Barr R G, Quek V S, Cousineau D, Oberlander T F, Brian J A, Young S N
Department of Pediatrics, McGill University, Montreal, Canada.
Dev Med Child Neurol. 1994 Jul;36(7):608-18. doi: 10.1111/j.1469-8749.1994.tb11898.x.
To determine whether a single intra-oral administration of sucrose would calm infants and elicit mouthing and hand-mouth contact, crying newborn and six-week-old infants were given sucrose solution before one feed and sterile water before another in a cross-over trial. Six-week-old infants were also given sucrose and water after feeding. For the newborn infants, the calming effect was rapid, substantial and lasted for at least four minutes. Mouthing and hand-mouth contact increased, but for shorter durations. For the six-week-old infants, sucrose calmed for one minute only before feeding, but had no effects on mouthing or hand-mouth contact. The results imply that intra-oral sucrose has acute age-related effects on crying and suckling-feeding behaviour mediated by a pre-absorptive mechanism. Sucrose may tap a functional system for reducing distress related to feeding and/or regulation of infant state.
为了确定单次口腔内给予蔗糖是否会使婴儿安静下来并引发舔舐及手口接触行为，在一项交叉试验中，给哭闹的新生儿和六周大的婴儿在一次喂食前给予蔗糖溶液，在另一次喂食前给予无菌水。六周大的婴儿在喂食后也给予了蔗糖和水。对于新生儿，这种安抚效果迅速且显著，持续至少四分钟。舔舐及手口接触有所增加，但持续时间较短。对于六周大的婴儿，蔗糖仅在喂食前使他们安静了一分钟，但对舔舐或手口接触没有影响。结果表明，口腔内给予蔗糖对哭闹和吸吮喂养行为具有与年龄相关的急性影响，这是由一种吸收前机制介导的。蔗糖可能利用了一个功能系统来减轻与喂养相关的痛苦和/或调节婴儿状态。
