Rachev E
Akush Ginekol (Sofiia). 1993;32(3):64-6.
The author presents his personal experience of treatment with a combination of natural estrogen--17 beta-oestradiol 2 mg and a gestagen--norethisterone acetate 1 mg on 38 climacteric women of mean age of 53.8 years. The effect on both climacteric symptoms (index of Kuppermann) and hormonal vaginal smears (karyopyknotic and maturation indices) was very good. The preparation Kliogest (Novo Nordisk A/S) appears to be one of the preparations of choice for HRT in postmenopausal women.