Keith L, Moss W, Berger G S
Am J Obstet Gynecol. 1975 Feb 1;121(3):399-404. doi: 10.1016/0002-9378(75)90020-4.
Among 2,019 women screened by triplicate culture technique, 191 (9.5 per cent) had one or more positive cultures of specimens for Neisseria gonorrhoeae. The prevalence rates by site of infection were as follows: cervix-8.1 per cent; rectum-2.4 per cent, and oropharynx-0.9 per cent. Of the 191 patients with gonorrhea, 163 (85 per cent) had a positive culture of the cervical specimen. Addition of routine cultures of rectal and oropharyngeal specimens detected only 15 per cent of positive cases, while tripling the cost of the screening program. Based on a cost-benefit anallysis, a culture of the cervical specimen is most appropriate for routine screening, and cultures of rectal and/or oropharyngeal specimens should be obtained on a selected basic only.
在采用三联培养技术筛查的2019名女性中，191人（9.5%）的淋病奈瑟菌标本培养结果呈阳性。按感染部位划分的患病率如下：宫颈——8.1%；直肠——2.4%，口咽部——0.9%。在191例淋病患者中，163人（85%）的宫颈标本培养结果呈阳性。增加直肠和口咽部标本的常规培养仅检测出15%的阳性病例，同时使筛查项目的成本增加了两倍。基于成本效益分析，宫颈标本培养最适合常规筛查，直肠和/或口咽部标本培养仅应在特定基础上进行。
