Lavond D G, Kanzawa S A, Ivkovich D, Clark R E
Department of Psychology, University of Southern California, Los Angeles 90089-2520.
Behav Neurosci. 1994 Apr;108(2):284-93. doi: 10.1037//0735-7044.108.2.284.
Unilateral lesion of the cerebellum in rabbits completely and permanently abolishes previous learning and prevents new learning ipsilateral to the lesion. However, when training continues on the contralateral side, there is substantial savings in that it takes few trials to learn. This observation may imply that the memory survives the lesion. Rabbits were classically conditioned for an eyelid response and then the ipsilateral interpositus nucleus of the cerebellum was lesioned. Then the rabbits were trained on the contralateral side. There is no savings on the contralateral side without first trying to train on the lesioned side. The authors conclude that the survival of a memory after the lesion probably does not account for the rapid transfer, but rather that the act of trying to train on the lesioned side in previous studies first induces a new memory on the contralateral side.
兔子小脑的单侧损伤会完全且永久性地消除先前的学习，并阻止损伤同侧的新学习。然而，当在对侧继续训练时，会有显著的节省效果，即只需很少的试验就能学会。这一观察结果可能意味着记忆在损伤后依然存在。对兔子进行经典条件反射训练以形成眼睑反应，然后损伤小脑同侧的间位核。接着在对侧对兔子进行训练。如果没有先在损伤侧进行训练，对侧就不会有节省效果。作者得出结论，损伤后记忆的留存可能无法解释快速转移现象，而是先前研究中在损伤侧进行训练的行为首先在对侧诱导出了新的记忆。
