Musoke A J, Williams J F
Immunology. 1975 Jan;28(1):97-101.
Mice were found to be protected against Taenia taeniaforMis infection by passive transfer of serum collected from donors 28 days after infection. The protective activity resided exclusively in the first fraction of 7S immunoglobulins eluting from DEAE-cellulose at pH 5.8 with 0.05 M phosphate buffer. This fraction contained 7Sgamma1 and 7Sgamma2 immunoglobulins but no detectable gammaA, gammaM or skin sensitizing activity. Fractions containing 7Sgamma 2 alone were ineffective in passive transfer.
研究发现,通过被动转移感染后28天从供体采集的血清,小鼠可免受泡状带绦虫感染。保护活性仅存在于用0.05M磷酸盐缓冲液在pH 5.8条件下从DEAE - 纤维素洗脱的7S免疫球蛋白的第一部分中。该部分含有7Sγ1和7Sγ2免疫球蛋白,但未检测到γA、γM或皮肤致敏活性。仅含7Sγ2的部分在被动转移中无效。