Kortmann R D, Hess C F, Jany R, Meisner C, Bamberg M
Department of Radiotherapy, University of Tübingen, Germany.
Int J Radiat Oncol Biol Phys. 1994 Jul 1;29(4):869-72. doi: 10.1016/0360-3016(94)90578-9.
Quantitative assessment of the accuracy of field alignment in a homogeneous group of patients with difficult positioning (postoperative irradiation after total hip replacement).
In 95 patients linear and rotational discrepancies were measured between the simulation and first check film and between five consecutive verification films.
For the total group of patients, all deviations were normally distributed with mean values of approximately zero and standard deviations of 4.0-8.0 mm (linear discrepancies) and 3.5-5 degrees (rotational discrepancies). Deviations were similar for the transition from simulator to the treatment machine and for subsequent treatment delivery, with 50% and 95% of absolute differences being less than 5 mm and 15 mm, respectively.
Our analysis indicates that statistical fluctuations are considerably more important than errors introduced at start of treatment. Therefore, a first check film seems to be inadequate to predict the expected inaccuracies for the whole course of treatment. In addition, our results should help to prescribe appropriate safety margins for patients with difficult positioning.
对一组定位困难的同质患者(全髋关节置换术后放疗)的射野对准精度进行定量评估。
对95例患者测量了模拟片与首次检查片之间以及五张连续验证片之间的线性和旋转偏差。
对于所有患者,所有偏差均呈正态分布,平均值约为零,标准差为4.0 - 8.0毫米(线性偏差)和3.5 - 5度(旋转偏差)。从模拟器到治疗机的转换以及后续治疗过程中的偏差相似,50%和95%的绝对差值分别小于5毫米和15毫米。
我们的分析表明,统计波动比治疗开始时引入的误差重要得多。因此,首次检查片似乎不足以预测整个治疗过程中预期的不准确性。此外,我们的结果应有助于为定位困难的患者规定适当的安全 margins。 (注:此处“安全 margins”表述不太准确,可能是“安全裕度”之类的意思,原文表述可能有误)