Shimanaka K, Kinoshita N, Iinuma H, Hamada M, Takeuchi T
Institute of Microbial Chemistry, Tokyo, Japan.
J Antibiot (Tokyo). 1994 Jun;47(6):668-74. doi: 10.7164/antibiotics.47.668.
Novel antibacterial antibiotics, amythiamicins A, B, C and D, have been isolated from the fermentation broth of Amycolatopsis sp. MI481-42F4. In this paper, the taxonomy of the producing strain, fermentation, isolation, physico-chemical properties and biological activities of amythiamicins are reported. Amythiamicins inhibit the growth of Gram-positive bacteria including multi-drug resistant strains.
新型抗菌抗生素A、B、C和D，已从拟无枝酸菌属MI481-42F4的发酵液中分离得到。本文报道了产生菌的分类学、发酵、分离、理化性质及A、B、C和D的生物活性。A、B、C和D对包括多重耐药菌株在内的革兰氏阳性菌的生长具有抑制作用。
