Young J J, Ho S N, Ju W M, Chang L R
Division of Applied Chemistry, National Defense Medical Center, Taipei, Taiwan, R.O.C.
J Antibiot (Tokyo). 1994 Jun;47(6):681-7. doi: 10.7164/antibiotics.47.681.
Six new kinamycin antibiotics have been isolated from the culture filtrate of Streptomyces chattanoogensis. The structures of six related components were determined employing 1D and 2D NMR spectroscopy and mass spectrometry. These structures represent the first reported epoxide kinamycin (2, 3) and propionyl derivative of kinamycin (5), and new isobutyryl derivatives of kinamycin (1, 4, 6).
从查塔努加链霉菌的培养滤液中分离出了六种新的北里霉素抗生素。利用一维和二维核磁共振光谱以及质谱法确定了六种相关成分的结构。这些结构代表了首次报道的环氧北里霉素（2,3）和北里霉素的丙酰衍生物（5），以及北里霉素的新异丁酰衍生物（1,4,6）。
