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既往外科瓣膜切开术后主动脉瓣球囊扩张术:即刻及随访结果

Balloon dilatation of the aortic valve after previous surgical valvotomy: immediate and follow up results.

作者信息

Sreeram N, Kitchiner D, Williams D, Jackson M

机构信息

Heart Clinic, Royal Liverpool Children's Hospital.

出版信息

Br Heart J. 1994 Jun;71(6):558-60. doi: 10.1136/hrt.71.6.558.

Abstract

OBJECTIVE

To evaluate the immediate and long-term results of transcatheter balloon dilatation of the aortic valve for restenosis after previous surgical valvotomy.

DESIGN

Prospective follow up by clinical examination and cross sectional Doppler echocardiography of all patients fulfilling the above criteria.

SETTING

Tertiary paediatric cardiology referral centre.

PATIENTS AND METHODS

22 patients (18 male, 4 female)--median (range) age 157.5 (12-254) months--underwent 25 balloon dilatation procedures at a median of 72 (8-155) months after surgery. The median age at surgical valvotomy was 82.5 (0.5-230) months and the systolic gradient across the aortic valve immediately after surgery was 31 (0-49) mm Hg. The indication for dilatation was a Doppler derived peak instantaneous gradient of > 60 mm Hg with grade 2 or less aortic regurgitation. A single balloon was used, and the median balloon to annulus ratio was 1 (0.9-1).

RESULTS

After dilatation the catheter pullback gradient decreased acutely from 55 (35-75) to 30 (0-75) mm Hg (p < 0.01) and the Doppler gradient from 74 (52-92) to 40.5 (30-96) mm Hg (p < 0.01). In three patients who underwent a second dilatation of the aortic valve eight months after the first procedure, the pullback gradient decreased from 50 (50-60) to 15 (15-16) mm Hg. Aortic regurgitation grade increased from 1 (0-2) to 2 (1-3); only one patient had grade 3 regurgitation. Over a median follow up of 33 (2-67) months seven patients had aortic valve replacement for recurrent stenosis (six patients) or severe regurgitation (one patient with grade 3 regurgitation after dilatation, who had partial detachment of one of the valve leaflets). There was no significant difference for the pullback gradient (median of 19 v 32.5 mm Hg), Doppler gradient 24 hours after dilatation (33.5 v 50.5 mm Hg; p = 0.03), or the duration of follow up (27.5 v 18 months) between the 12 patients who did not require further dilatation or surgery and the 10 patients who did.

CONCLUSIONS

Balloon dilatation of the aortic valve is a safe and feasible option for palliation of restenosis after surgical valvotomy for congenital aortic valve stenosis. In many patients, however, stenosis progressed and a further intervention was required.

摘要

目的

评估经导管球囊扩张术治疗既往外科瓣膜切开术后主动脉瓣再狭窄的近期和远期效果。

设计

对所有符合上述标准的患者进行临床检查和横断面多普勒超声心动图的前瞻性随访。

地点

三级儿科心脏病转诊中心。

患者和方法

22例患者(18例男性,4例女性),年龄中位数(范围)为157.5(12 - 254)个月,在术后中位数72(8 - 155)个月接受了25次球囊扩张术。外科瓣膜切开术时的年龄中位数为82.5(0.5 - 230)个月,术后即刻主动脉瓣跨瓣收缩期压差为31(0 - 49)mmHg。扩张的指征是多普勒测量的峰值瞬时压差>60mmHg且主动脉瓣反流≤2级。使用单个球囊,球囊与瓣环直径比中位数为1(0.9 - 1)。

结果

扩张后导管回撤压差从55(35 - 75)mmHg急剧降至30(0 - 75)mmHg(p < 0.01),多普勒压差从74(52 - 92)mmHg降至40.5(30 - 96)mmHg(p < 0.01)。3例患者在首次手术后8个月接受了第二次主动脉瓣扩张,导管回撤压差从50(50 - 60)mmHg降至15(15 - 16)mmHg。主动脉瓣反流分级从1(0 - 2)级升至2(1 - 3)级;仅1例患者为3级反流。在中位数为33(2 - 67)个月的随访期内,7例患者因再狭窄(6例)或严重反流(1例扩张后3级反流患者,其一个瓣叶部分脱垂)接受了主动脉瓣置换术。在无需进一步扩张或手术的12例患者与需要进一步干预的10例患者之间,导管回撤压差(中位数分别为19与32.5mmHg)、扩张后24小时的多普勒压差(33.5与50.5mmHg;p = 0.03)或随访时间(27.5与18个月)无显著差异。

结论

对于先天性主动脉瓣狭窄外科瓣膜切开术后再狭窄的姑息治疗,球囊扩张主动脉瓣是一种安全可行的选择。然而,在许多患者中,狭窄仍会进展,需要进一步干预。

相似文献

本文引用的文献

1
Repeat aortic valvotomy in children.
Am Heart J. 1983 Jul;106(1 Pt 1):60-3. doi: 10.1016/0002-8703(83)90440-4.
2
Percutaneous balloon aortic valvuloplasty: results in 23 patients.
Am J Cardiol. 1984 Jan 1;53(1):194-7. doi: 10.1016/0002-9149(84)90709-4.
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Long-term follow-up of valvotomy before 1968 for congenital aortic stenosis.
Am J Cardiol. 1986 Aug 1;58(3):338-41. doi: 10.1016/0002-9149(86)90073-1.
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Short- and midterm results of balloon valvuloplasty for valvular aortic stenosis in children.
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