Kotani K, Tokunaga K, Fujioka S, Kobatake T, Keno Y, Yoshida S, Shimomura I, Tarui S, Matsuzawa Y
Second Department of Internal Medicine, Osaka University Medical School, Japan.
Int J Obes Relat Metab Disord. 1994 Apr;18(4):207-2.
We performed a cross-sectional study using whole-body computerized tomographic (CT) scans in order to clarify age-related changes in whole-body fat distribution in both genders. The subjects were 66 men and 96 women, whose body mass index (BMI) was over 25 kg/m2. CT scans were performed at seven levels (head, fore-arms, upper arms, chest, abdomen, thighs and calves), and the fat volumes of the segments were calculated from the cross-sectional areas of the fat tissues. After calibrating to the total fat volumes, the relationship between age and the relative segmental fat volumes was analysed. In both genders, the relative intra-abdominal visceral fat volume increased and that of the legs decreased with age. The relative abdominal subcutaneous fat volume decreased with age only in male subjects. The increase in the relative visceral fat volume with age was about 2.6 times larger in males than in pre-menopausal females, while post-menopausal females showed the same increase as male subjects. These data suggest that there is a definite gender difference in the age-related changes in whole-body fat distribution, especially in the abdominal fat tissues. In addition, the accumulation of visceral fat is markedly accelerated by menopause in women.
我们进行了一项横断面研究，使用全身计算机断层扫描（CT）来阐明两性全身脂肪分布的年龄相关变化。研究对象为66名男性和96名女性，其体重指数（BMI）超过25kg/m²。在七个层面（头部、前臂、上臂、胸部、腹部、大腿和小腿）进行CT扫描，并根据脂肪组织的横截面积计算各部位的脂肪体积。在校正为总脂肪体积后，分析年龄与相对节段性脂肪体积之间的关系。在两性中，相对腹内内脏脂肪体积随年龄增加而增加，腿部的相对脂肪体积随年龄减少。仅在男性受试者中，相对腹部皮下脂肪体积随年龄减少。随着年龄增长，男性相对内脏脂肪体积的增加比绝经前女性大约大2.6倍，而绝经后女性与男性受试者的增加幅度相同。这些数据表明，在全身脂肪分布的年龄相关变化中存在明显的性别差异，尤其是在腹部脂肪组织中。此外，女性绝经后内脏脂肪的积累明显加速。
