沙丁胺醇生产工人中的职业性哮喘
Occupational asthma in salbutamol process workers.
作者信息
Agius R M, Davison A G, Hawkins E R, Newman Taylor A J
机构信息
Department of Public Health Sciences, University of Edinburgh Medical School, UK.
出版信息
Occup Environ Med. 1994 Jun;51(6):397-9. doi: 10.1136/oem.51.6.397.
Abstract
Occupational asthma after exposure to salbutamol in the pharmaceutical industry has not been previously reported. The occurrence of occupational asthma is described in two pharmaceutical process workers who were likely to have inhaled doses appreciably in excess of the therapeutic dose range. The findings do not lead to an unequivocal conclusion on the mechanism of the asthma but it was probably a pharmacological consequence of high exposure.
摘要
制药行业接触沙丁胺醇后发生职业性哮喘此前未见报道。本文描述了两名制药工艺工人发生职业性哮喘的情况，他们可能吸入了明显超过治疗剂量范围的剂量。这些发现并未就哮喘的发病机制得出明确结论，但可能是高暴露的药理学后果。
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