Wilson D M, Killen J D, Hayward C, Robinson T N, Hammer L D, Kraemer H C, Varady A, Taylor C B
Department of Pediatrics, Stanford (Calif) University.
Arch Pediatr Adolesc Med. 1994 Aug;148(8):789-95. doi: 10.1001/archpedi.1994.02170080019004.
To test the hypothesis that the patterns of pubertal progression, early vs late puberty and fast vs slow, are associated with the age at which girls start to drink alcohol and smoke cigarettes.
The study included 1463 female students, 10.7 to 18.2 years of age, who were assessed five times during the 2.7-year study. Data regarding pubertal stage, alcohol use, and cigarette use were obtained at each assessment. These data were used to calculate two indexes of pubertal development, the age at which the midpoint of puberty was achieved and the rate of progression through puberty, and the ages when each subject first drank, first drank moderate amounts of alcohol, and first smoked.
Girls with earlier puberty (midpoint < 12.2 years) first reported drinking any alcohol at a median age of 12.5 years, 0.7 years younger than girls whose puberty was later. Similarly, girls with earlier puberty reported drinking moderate amounts of alcohol at a median age of 13.7 years, 0.9 years younger than girls with later puberty. Girls with earlier puberty further reported first smoking cigarettes at a median age of 12.8 years, 0.6 years younger than girls with later puberty. The rate of pubertal progression was significantly associated only with the age when girls first drank moderate amounts of alcohol.
Earlier puberty is associated with a younger age of onset for both drinking and smoking among adolescent girls.
检验青春期发育模式（青春期早发与晚发、快速进展与缓慢进展）与女孩开始饮酒和吸烟的年龄相关的假设。
该研究纳入了1463名年龄在10.7至18.2岁之间的女学生，在为期2.7年的研究中对她们进行了五次评估。每次评估时获取有关青春期阶段、饮酒情况和吸烟情况的数据。这些数据用于计算两个青春期发育指标，即达到青春期中点的年龄和青春期进展速度，以及每个受试者首次饮酒、首次饮用适量酒精和首次吸烟的年龄。
青春期较早（中点年龄<12.2岁）的女孩首次报告饮酒的中位年龄为12.5岁，比青春期较晚的女孩小0.7岁。同样，青春期较早的女孩报告饮用适量酒精的中位年龄为13.7岁，比青春期较晚的女孩小0.9岁。青春期较早的女孩还报告首次吸烟的中位年龄为12.8岁，比青春期较晚的女孩小0.6岁。青春期进展速度仅与女孩首次饮用适量酒精的年龄显著相关。
青春期较早与青春期女孩饮酒和吸烟的起始年龄较小有关。
