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[间接血凝抑制反应作为滴定免疫血清的一种方法。V. 该反应在人血清中免疫球蛋白A、M和G定量测定中的应用]

[Indirect hemagglutination inhibition reactions as a method of titrating immune serums. V. Application of the reaction to the quantitative determination of immunoglobulins A, M and G in human blood sera].

作者信息

Konikova R E, Semenova B N, Noskov F S, Shakhanina K L, Malkina L A

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1975 Jan(1):42-4.

PMID:804778
Abstract

The authors present the results of using the indirect hemagglutination inhibition test (IHIT) for quantitative determination of A, M and G immunoglobulins in the blood sera of humans in comparison with the method of radial immunodiffusion in agar (RID) after Mancini. The results of IHIT were no less precise and reproducible than those of RID. The significance of the correlation coefficient of grades after Spirman constituted greater than 99.9% for both tests. On this basis a conclusion was made that, having a number of advantages over RID, IHIT could be recommended for quantitative titration of immunoglobulins of various classes.

摘要

作者介绍了使用间接血凝抑制试验(IHIT)定量测定人血清中A、M和G免疫球蛋白的结果,并与曼奇尼法琼脂免疫扩散试验(RID)进行比较。IHIT的结果与RID的结果同样精确且可重复。两种试验的斯皮尔曼等级相关系数的显著性均大于99.9%。在此基础上得出结论,IHIT比RID有许多优势,可推荐用于各类免疫球蛋白的定量滴定。

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