Struve J, Aronsson B, Frenning B, Forsgren M, Weiland O
Dept. of Infectious Disease, Karolinska Institute, Huddinge Hospital, Sweden.
Scand J Gastroenterol. 1994 Apr;29(4):360-2. doi: 10.3109/00365529409094850.
The prevalence of hepatitis C virus (HCV) markers was investigated among health care staff with a high rate of exposure to blood or needle-stick injuries. After screening sera in pools of 10 at a time and individual testing of all reactive pools, totally 6 of 880 (0.7%; 95% confidence interval, 0.25-14.8%) were positive for anti-HCV, a figure of the same order as that found among Swedish first-time blood donors. Among the seropositives, all of five evaluable had been exposed to blood and four of five to needle-stick injuries. Our data suggest that HCV, in addition to hepatitis B virus, may constitute an occupational hazard for health care workers in Stockholm, even though the risk appears to be low, and personal risk factors such as intravenous drug abuse or blood transfusion could not be ruled out as sources of the infection.
在接触血液或针刺伤发生率较高的医护人员中，对丙型肝炎病毒（HCV）标志物的流行情况进行了调查。在每次将血清以10份为一组进行筛查并对所有反应性组进行个体检测后，880名医护人员中有6名（0.7%；95%置信区间，0.25 - 14.8%）抗HCV呈阳性，这一数字与瑞典首次献血者中发现的数字处于同一水平。在血清阳性者中，5名可评估者均接触过血液，5名中有4名曾发生针刺伤。我们的数据表明，除了乙型肝炎病毒外，HCV可能也是斯德哥尔摩医护人员面临的一种职业危害，尽管风险似乎较低，并且不能排除静脉药物滥用或输血等个人风险因素作为感染源。
