DeGuzman L J, Pitrak D L, Dawson G J, Shin D C, Holzer T J, Layden T J
Section of Digestive and Liver Diseases, University of Illinois at Chicago.
Dig Dis Sci. 1994 Aug;39(8):1691-3. doi: 10.1007/BF02087777.
Acute hepatitis E infection was diagnosed in a Pakistani immigrant admitted to the University of Illinois Hospital. Utilizing enzyme immunoassay (EIA) tests, specific IgG and IgM class antibodies to three different epitopes of hepatitis E virus (HEV) were detected 12 weeks after the onset of illness and in the early convalescent stage. Sixteen months after the onset of hepatitis, IgM anti-HEV was no longer detectable. Low levels of IgG class anti-HEV antibodies continued to be detected. We demonstrate the utility of the EIA HEV assay to diagnose prospectively acute HEV infection.
一名入住伊利诺伊大学医院的巴基斯坦移民被诊断为急性戊型肝炎感染。利用酶免疫测定（EIA）检测，在发病12周后及早期恢复期检测到针对戊型肝炎病毒（HEV）三种不同表位的特异性IgG和IgM类抗体。肝炎发病16个月后，IgM抗HEV不再能检测到，但仍能检测到低水平的IgG类抗HEV抗体。我们证明了EIA HEV检测在前瞻性诊断急性HEV感染中的实用性。
