Wada Y, Nakatsu A, Kondo T
Department of Ophthalmology, Kobe City General Hospital, Japan.
Ophthalmic Surg. 1994 May;25(5):317-20.
We retrospectively reviewed the records of patients followed for over 4 years after undergoing trabeculotomy to treat primary open-angle glaucoma (POAG) to evaluate the long-term effects of the procedure on intraocular pressure (IOP) control. IOP remained below 15 mm Hg, with no need for postoperative medication in 7 (13.2%) of 53 eyes. IOP was below 15 mm Hg in an additional eight eyes (15.1%) treated with topical medication. Topical medication was needed to maintain IOP between 16 to 20 mm Hg in 23 eyes (43.4%). Oral acetazolamide or additional surgery was needed in 15 (28.3%). A postoperative IOP below 20 mm Hg with or without topical medication was associated with a survival probability of 71.2%. Our results demonstrated that, although trabeculotomy largely failed to maintain an "ideal" postoperative IOP (below 15 mm Hg), it was not associated with severe operative or postoperative complications such as flat anterior chamber. Thus, the procedure probably should be the first choice not only in uncomplicated cases of congenital glaucoma and pseudoexfoliation glaucoma (as previously established), but also in cases of POAG in young patients with only slight damage to the optic disc or visual field and cases with forward movement of the iris-lens diaphragm.
我们回顾性分析了接受小梁切开术治疗原发性开角型青光眼(POAG)后随访超过4年的患者记录,以评估该手术对眼压(IOP)控制的长期效果。53眼中有7眼(13.2%)眼压维持在15 mmHg以下,无需术后用药。另有8眼(15.1%)使用局部药物治疗后眼压低于15 mmHg。23眼(43.4%)需要局部用药将眼压维持在16至20 mmHg之间。15眼(28.3%)需要口服乙酰唑胺或再次手术。无论是否使用局部药物,术后眼压低于20 mmHg的患者生存概率为71.2%。我们的结果表明,尽管小梁切开术在很大程度上未能维持“理想”的术后眼压(低于15 mmHg),但它与诸如无前房等严重的手术或术后并发症无关。因此,该手术不仅可能应作为先天性青光眼和假性剥脱性青光眼单纯病例(如先前确定的)的首选,也应作为年轻原发性开角型青光眼患者中仅对视盘或视野有轻微损害的病例以及虹膜 - 晶状体隔前移病例的首选。