Boswell W C, Zoller M, Williams J S, Lord S A, Check W
Department of Surgery, Memorial Medical Center, Savannah, Georgia 31403-3089.
Am Surg. 1994 Sep;60(9):650-5.
The thyroid gland originates from the foramen cecum, and by 7 weeks gestation, descends ventrally in the midline of the neck. During its descent, a patent diverticulum, the thyroglossal duct, connects the gland to the base of the tongue. While the duct normally closes by the tenth gestational week, it is not uncommon to have all or a portion of the duct remain patent as a thyroglossal duct cyst or sinus. While these cysts are relatively common, thyroglossal duct carcinomas are very uncommon. They are generally of two types: squamous cell carcinoma arising from metaplastic columnar cells, and thyrogenic carcinoma arising from thyroembryonic rests in the duct or cyst. We report one case of each. The squamous cell carcinoma was resected via the Sistrunk procedure with no evidence of recurrence over a 10-year follow-up. The thyrogenic carcinoma (papillary type) was resected via the Sistrunk procedure with subsequent total thyroidectomy.
甲状腺起源于盲孔，在妊娠7周时沿颈部中线腹侧下降。在其下降过程中，一个通畅的憩室，即甲状舌管，将腺体与舌根相连。虽然该导管通常在妊娠第10周时闭合，但导管全部或部分保持通畅形成甲状舌管囊肿或窦的情况并不少见。虽然这些囊肿相对常见，但甲状舌管癌却非常罕见。它们通常有两种类型：由化生柱状细胞引起的鳞状细胞癌，以及由导管或囊肿中的甲状腺胚胎残余引起的甲状腺源性癌。我们各报告一例。鳞状细胞癌通过Sistrunk手术切除，在10年的随访中无复发迹象。甲状腺源性癌（乳头状型）通过Sistrunk手术切除，随后进行全甲状腺切除术。
