Paajanen H, Lehto I, Alanen A, Erkintalo M, Komu M
Department of Orthopedic Surgery, University Hospital of Tampere, Finland.
J Orthop Res. 1994 Jul;12(4):509-14. doi: 10.1002/jor.1100120407.
The feasibility of magnetic resonance imaging and the magnetization transfer technique for measurement of diurnal fluid changes in lumbar discs was studied with the use of 13 healthy subjects. The diurnal height loss of the subjects ranged from 13 to 21 mm. The disc signal in T2-weighted magnetic resonance imaging increased as much as 25% after overnight bed rest, presumably due to the enhanced influx of water. The change in magnetization transfer parameters also suggested increased hydration of the disc after bed rest. Magnetic resonance imaging techniques can be used for indirect measurement of the changes in fluid content and the interaction of water with macromolecules in the disc.
利用13名健康受试者研究了磁共振成像和磁化传递技术测量腰椎间盘日间液体变化的可行性。受试者的日间身高损失范围为13至21毫米。在夜间卧床休息后，T2加权磁共振成像中的椎间盘信号增加了多达25%，这可能是由于水的流入增加所致。磁化传递参数的变化也表明卧床休息后椎间盘的水合作用增强。磁共振成像技术可用于间接测量椎间盘内液体含量的变化以及水与大分子之间的相互作用。
