通过T淋巴细胞产物激活小鼠腹腔细胞以杀死单核细胞增生李斯特菌。
Activation of mouse peritoneal cells to kill Listeria monocytogenes by T-lymphocyte products.
作者信息
Cole P
出版信息
Infect Immun. 1975 Jul;12(1):36-41. doi: 10.1128/iai.12.1.36-41.1975.
Abstract
An in vitro system has been used to demonstrate that glass-adherent mouse peritoneal cells can be activated to kill intracellular Listeria monocytogenes by antigen-stimulated T-lymphocytes derived from immunized mice. The soluble products of such stimulated lymphocyte cultures could only be shown to similarly activate peritoneal cells if the antigen used in both the immunization and lymphocyte stimulation was also present on the target intracellular organism.
摘要
已使用体外系统证明，玻璃黏附的小鼠腹腔细胞可被来自免疫小鼠的抗原刺激T淋巴细胞激活，以杀死细胞内的单核细胞增生李斯特菌。只有当免疫和淋巴细胞刺激中使用的抗原也存在于靶细胞内生物体上时，这种刺激淋巴细胞培养物的可溶性产物才能同样激活腹腔细胞。
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