Rafuse P E, Mills D W, Hooper P L, Chang T S, Wolf R
Department of Ophthalmology, Dalhousie University, Halifax, NS.
Can J Ophthalmol. 1994 Apr;29(2):73-6.
We examined the effects of breath holding against a closed glottis (Valsalva's manoeuvre) on intraocular pressure (IOP) in four groups of volunteer subjects: 37 healthy young control subjects, 10 patients with chronic open-angle glaucoma, 11 age-matched control subjects and 8 glaucoma suspects. IOP was recorded by one person using a Digilab 30R/T Pneuma-Tonometer. Chart recordings of the IOP were measured independently by a second investigator. Recordings were taken before, during and 5 minutes after the seated subject exhaled into an aneroid manometer to a pressure of 25 to 35 cm H2O. There was marked variability in the individual responses to Valsalva's manoeuvre in all four groups, with substantial increases (to +9.5 mm Hg) and decreases (to -4.0 mm Hg) in IOP seen. The mean change in IOP during Valsalva's manoeuvre was a small, statistically insignificant decrease in all four groups. The mean change in IOP following Valsalva's manoeuvre was a larger, but still clinically small, decrease. The clinician should be aware of the individual variability in IOP changes with Valsalva's manoeuvre.
我们在四组志愿者中研究了闭声门屏气（瓦尔萨尔瓦动作）对眼压（IOP）的影响：37名健康年轻对照者、10名慢性开角型青光眼患者、11名年龄匹配的对照者和8名青光眼疑似患者。由一人使用Digilab 30R/T气动眼压计记录眼压。眼压的图表记录由另一名研究人员独立测量。在坐着的受试者向无液压力计呼气至压力为25至35 cm H2O之前、期间和之后5分钟进行记录。在所有四组中，个体对瓦尔萨尔瓦动作的反应存在显著差异，眼压有大幅升高（至+9.5 mmHg）和降低（至-4.0 mmHg）的情况。在瓦尔萨尔瓦动作期间，眼压的平均变化在所有四组中均为小幅下降，无统计学意义。瓦尔萨尔瓦动作后眼压的平均变化为更大幅度的下降，但临床上仍较小。临床医生应意识到瓦尔萨尔瓦动作引起的眼压变化存在个体差异。
