Radmacher M, Cleveland J P, Fritz M, Hansma H G, Hansma P K
Physics Department, University of California, Santa Barbara 83106.
Biophys J. 1994 Jun;66(6):2159-65. doi: 10.1016/S0006-3495(94)81011-2.
Force curves were recorded as the sample was raster-scanned under the tip. This opens new opportunities for imaging with the atomic force microscope: several characteristics of the samples can be measured simultaneously, for example, topography, adhesion forces, elasticity, van der Waals, and electrostatic interactions. The new opportunities are illustrated by images of several characteristics of thin metal films, aggregates of lysozyme, and single molecules of DNA.
当样品在探针下进行光栅扫描时记录力曲线。这为原子力显微镜成像带来了新机遇:可以同时测量样品的几个特性,例如形貌、粘附力、弹性、范德华力和静电相互作用。通过金属薄膜、溶菌酶聚集体和DNA单分子的几个特性的图像说明了这些新机遇。