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Evidence of pestivirus RNA in human virus vaccines.

作者信息

Harasawa R, Tomiyama T

机构信息

Animal Center for Biomedical Research, Faculty of Medicine, University of Tokyo, Japan.

出版信息

J Clin Microbiol. 1994 Jun;32(6):1604-5. doi: 10.1128/jcm.32.6.1604-1605.1994.

DOI:10.1128/jcm.32.6.1604-1605.1994
PMID:8077414
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC264050/
Abstract

We examined live virus vaccines against measles, mumps, and rubella for the presence of pestivirus RNA or of pestiviruses by reverse transcription PCR. Pestivirus RNA was detected in two measles-mumps-rubella combined vaccines and in two monovalent vaccines against mumps and rubella. Nucleotide sequence analysis of the PCR products indicated that a modified live vaccine strain used for immunization of cattle against bovine viral diarrhea is not responsible for the contamination of the vaccines.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e99/264050/38997da98081/jcm00006-0198-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e99/264050/38997da98081/jcm00006-0198-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e99/264050/38997da98081/jcm00006-0198-a.jpg

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Bovine viral diarrhoea virus infections in piglets born to sows vaccinated against swine fever with contaminated vaccine.
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