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酒精性硬化治疗多囊肝疾病和阻塞性黄疸:鼻胆管导管的应用

Alcohol sclerosis for polycystic liver disease and obstructive jaundice: use of a nasobiliary catheter.

作者信息

Dumot J A, Fields M S, Meyer R A, Shay S S, Conwell D L, Brzezinski A

机构信息

Department of Internal Medicine, Cleveland Clinic Foundation, Ohio.

出版信息

Am J Gastroenterol. 1994 Sep;89(9):1555-7.

PMID:8079938
Abstract

We report the use of a nasobiliary catheter in the management of a 55-yr-old female with autosomal dominant polycystic kidney disease who developed obstructive jaundice from a hepatic cyst. The patient presented with a 2-wk history of fatigue, jaundice, nausea, vomiting, and abdominal pain. Physical examination was remarkable for tender hepatomegaly. Computerized tomography revealed multiple hepatic cysts and dilated intrahepatic biliary radicles. Endoscopic stent placement failed to relieve the obstruction. Computerized tomography guided percutaneous aspiration of the obstructing hepatic cyst was successful with the aid of a nasobiliary cholangiogram allowing visualization of the biliary tree and identification of the obstructing hepatic cyst. However, the cyst rapidly accumulated fluid, and the obstruction recurred within 1 wk of simple aspiration. Relief of symptoms was maintained only after alcohol sclerosis of the obstructing hepatic cyst. Review of the literature shows that alcohol sclerotherapy is a safe and effective nonsurgical means of treating symptomatic hepatic cysts.

摘要

我们报告了一例使用鼻胆管导管治疗的病例,患者为一名55岁的女性,患有常染色体显性多囊肾病,因肝囊肿导致梗阻性黄疸。患者出现疲劳、黄疸、恶心、呕吐和腹痛2周病史。体格检查显示肝脏肿大且有压痛。计算机断层扫描显示多个肝囊肿和肝内胆管分支扩张。内镜下放置支架未能缓解梗阻。在鼻胆管造影的辅助下,计算机断层扫描引导经皮穿刺抽吸梗阻性肝囊肿成功,从而能够观察胆管树并识别梗阻性肝囊肿。然而,囊肿迅速积液,单纯抽吸后1周内梗阻复发。仅在对梗阻性肝囊肿进行酒精硬化治疗后症状才得以缓解。文献回顾表明,酒精硬化疗法是治疗有症状肝囊肿的一种安全有效的非手术方法。

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