de Virgilio C, Verbin C, Chang L, Linder S, Stabile B E, Klein S
Department of Surgery, Harbor-University of California-Los Angeles Medical Center, Torrance.
Arch Surg. 1994 Sep;129(9):909-12; discussion 912-3. doi: 10.1001/archsurg.1994.01420330023005.
To evaluate the efficacy of endoscopic retrograde cholangiopancreatography (ERCP) and laparoscopic cholecystectomy in patients with gallstone pancreatitis and to determine criteria predictive of common bile duct stones (CBDS).
Retrospective chart review.
Seventy-one consecutive patients with gallstone pancreatitis.
Identification and endoscopic management of CBDS, complications, and mortality.
Preoperatively, ERCP revealed CBDS in seven of 22 patients and postoperatively, in five of six patients. All stones were successfully removed. Laboratory values and common bile duct dilatation on admission did not predict CBDS. Persistent hyperamylasemia (> 150 U/L) and persistent hyperbilirubinemia (> 29.07 mumol/L [1.7 mg/dL]) were associated with CBDS on ERCP or intraoperative cholangiography. All five patients with cholangitis underwent ERCP, and CBDS were found and removed in four. There were no deaths and there was a 7% complication rate.
Gallstone pancreatitis can be effectively managed by selective ERCP, endoscopic sphincterotomy, and laparoscopic cholecystectomy. Preoperative ERCP can be restricted to patients with cholangitis, persistent hyperbilirubinemia, or persistent hyperamylasemia.
评估内镜逆行胰胆管造影术(ERCP)和腹腔镜胆囊切除术治疗胆石性胰腺炎患者的疗效,并确定预测胆总管结石(CBDS)的标准。
回顾性病历审查。
71例连续性胆石性胰腺炎患者。
CBDS的识别与内镜处理、并发症及死亡率。
术前,22例患者中有7例经ERCP发现CBDS,术后,6例患者中有5例发现。所有结石均成功取出。入院时的实验室值和胆总管扩张情况无法预测CBDS。持续性高淀粉酶血症(>150 U/L)和持续性高胆红素血症(>29.07 μmol/L [1.7 mg/dL])与ERCP或术中胆管造影发现的CBDS相关。所有5例胆管炎患者均接受了ERCP,其中4例发现并取出了CBDS。无死亡病例,并发症发生率为7%。
胆石性胰腺炎可通过选择性ERCP、内镜括约肌切开术和腹腔镜胆囊切除术有效治疗。术前ERCP可仅限于胆管炎、持续性高胆红素血症或持续性高淀粉酶血症患者。