Mani S, Duffy T P
Department of Internal Medicine, Yale University School of Medicine, New Haven, Conn.
Chest. 1994 Sep;106(3):967-70. doi: 10.1378/chest.106.3.967.
We report four cases of malignant pleuropericardial effusions in patients with chronic phase myelomonocytic leukemia (CMML). Based on current literature, this event is rare and very poorly understood. Our cases shed light on three important clinical characteristics: (1) patients with CMML develop effusions during uncontrolled leukocytosis; (2) these effusions are very responsive to conventional chemotherapy; and (3) effusions may develop without clinical forms of disease in other sites of extramedullary hematopoiesis.
我们报告了4例慢性粒单核细胞白血病（CMML）患者出现恶性胸膜心包积液的病例。根据目前的文献，这种情况很罕见，人们对此了解甚少。我们的病例揭示了三个重要的临床特征：（1）CMML患者在白细胞增多未得到控制时出现积液；（2）这些积液对传统化疗反应非常敏感；（3）积液可能在没有其他髓外造血部位疾病临床症状的情况下出现。
