Firth N, Fink P D, Johnson L, Skurray R A
School of Biological Sciences, University of Sydney, New South Wales, Australia.
J Bacteriol. 1994 Sep;176(18):5871-3. doi: 10.1128/jb.176.18.5871-5873.1994.
The traH gene of the staphylococcal conjugative plasmid pSK41 has recently been shown to encode a lipoprotein (N. Firth, K. P. Ridgway, M. E. Byrne, P. D. Fink, L. Johnson, I. T. Paulsen, and R. A. Skurray, Gene 136:13-25, 1993). Here we report that traH encodes a product recognized as a pheromone by Enterococcus faecalis cells harboring the conjugative plasmid pAD1. The mature traH product is not essential for this phenomenon, as expression of pheromone-like activity was found to require sequences encoding only the pro-TraH signal peptide.
葡萄球菌接合质粒pSK41的traH基因最近已被证明编码一种脂蛋白(N. 弗思、K. P. 里奇韦、M. E. 伯恩、P. D. 芬克、L. 约翰逊、I. T. 保尔森和R. A. 斯库里,《基因》136:13 - 25,1993年)。在此我们报告,traH编码一种被携带接合质粒pAD1的粪肠球菌细胞识别为信息素的产物。成熟的traH产物对于这种现象并非必不可少,因为发现信息素样活性的表达仅需要编码前TraH信号肽的序列。