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经前情绪变化易感性:抑郁障碍既往史的相关性。

Vulnerability to perimenstrual mood change: the relevance of a past history of depressive disorder.

作者信息

Bancroft J, Rennie D, Warner P

机构信息

Behaviour Research Group, MRC Reproductive Biology Unit, Royal Edinburgh Hospital, United Kingdom.

出版信息

Psychosom Med. 1994 May-Jun;56(3):225-31. doi: 10.1097/00006842-199405000-00008.

DOI:10.1097/00006842-199405000-00008
PMID:8084968
Abstract

A past history of depressive illness, defined in terms of treatment by antidepressants, was found to be more common in women seeking help for premenstrual syndrome (PMS) (31.3%; N = 83) than in women complaining of menorrhagia (8.9%; N = 90) or controls (5.8%; N = 104) with dysmenorrhea sufferers (22%; N = '50) reporting intermediate rates. Such a history in the clinical groups was associated with a tendency for premenstrual depression to be relatively prolonged (i.e., persisting through the menstrual phase and sometimes into the postmenstrual week) and with more severe depressive symptoms during the premenstrual, menstrual, and to a lesser extent, postmenstrual phases of the cycle. This, association was not evident for reported heaviness of menstrual bleeding and only weakly evident for severity of pain during the menstrual phase. Women with a depressive history gave higher neuroticism scores. A history of depression, as defined, seems to increase the vulnerability of women to depressive perimenstrual mood change in terms of both duration and severity. This effect on duration may hitherto have served to obscure the relationship between history of depression and premenstrual syndrome.

摘要

研究发现,有抑郁症病史(以服用抗抑郁药治疗来界定)的女性在因经前综合征(PMS)寻求帮助的女性中更为常见(31.3%;N = 83),高于主诉月经过多的女性(8.9%;N = 90)或痛经对照组女性(5.8%;N = 104),痛经患者的这一比例为22%(N = 50),处于中间水平。临床组中的此类病史与经前抑郁相对延长的趋势相关(即持续到月经期,有时持续到月经后期),且在月经周期的经前期、月经期以及程度稍轻的月经后期,抑郁症状更为严重。这种关联在报告的月经量方面不明显,在月经期疼痛严重程度方面仅有微弱体现。有抑郁病史的女性神经质得分更高。如所界定的那样,抑郁症病史似乎会使女性在抑郁性经前情绪变化的持续时间和严重程度方面更易受影响。这种对持续时间的影响可能迄今掩盖了抑郁症病史与经前综合征之间的关系。

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