一名患有咽颈臂型吉兰-巴雷综合征的患者体内的两种抗神经节苷脂抗体。
Two species of antiganglioside antibodies in a patient with a pharyngeal-cervical-brachial variant of Guillain-Barré syndrome.
作者信息
Mizoguchi K, Hase A, Obi T, Matsuoka H, Takatsu M, Nishimura Y, Irie F, Seyama Y, Hirabayashi Y
机构信息
Department of Neurology, National Shizuoka Hospital, Japan.
出版信息
J Neurol Neurosurg Psychiatry. 1994 Sep;57(9):1121-3. doi: 10.1136/jnnp.57.9.1121.
Abstract
A patient with a pharyngeal-cervical-brachial variant of Guillain-Barré syndrome had anti-GT1a and anti-GD1a antibodies (IgG) in the serum. The activities of anti-GT1a antibodies were stronger than anti-GD1a antibodies and their activities declined later in the clinical course. These two different antibodies bound independently to each ganglioside in an absorption study with polystyrene beads coated with GT1a or GD1a.
摘要
一名患有咽-颈-臂型吉兰-巴雷综合征的患者血清中存在抗GT1a和抗GD1a抗体（IgG）。抗GT1a抗体的活性强于抗GD1a抗体，且在临床病程后期其活性下降。在一项用包被有GT1a或GD1a的聚苯乙烯珠进行的吸收研究中，这两种不同的抗体分别独立地与各神经节苷脂结合。
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