分枝杆菌属和链霉菌属中的四环素抗性决定因素。
Tetracycline resistance determinants in Mycobacterium and Streptomyces species.
作者信息
Pang Y, Brown B A, Steingrube V A, Wallace R J, Roberts M C
机构信息
Department of Pathobiology, University of Washington, Seattle 98195.
出版信息
Antimicrob Agents Chemother. 1994 Jun;38(6):1408-12. doi: 10.1128/AAC.38.6.1408.
Two of seven tetracycline-resistant (Tcr) Mycobacterium fortuitum group isolates and six Tcr clinical Streptomyces isolates carried gram-positive Tcr determinants (Tet K and Tet L) and Streptomyces resistance determinants (Otr A, Otr B, and Otr C). This represents the first documentation of the acquisition by mycobacteria of determinants coding for antibiotic resistance and suggests the potential for the spread of antibiotic resistance determinants within mycobacterial species.
7株四环素抗性（Tcr）偶然分枝杆菌属菌株中的2株以及6株Tcr临床链霉菌菌株携带革兰氏阳性Tcr决定簇（Tet K和Tet L）和链霉菌抗性决定簇（Otr A、Otr B和Otr C）。这是分枝杆菌获得编码抗生素抗性决定簇的首次记录，并提示了抗生素抗性决定簇在分枝杆菌种内传播的可能性。
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