Osei Sekyere John
Department of Pharmaceutics, Faculty of Pharmacy and Pharmaceutical Sciences, KNUST, Kumasi, Ghana ; Department of Pharmacy, University of KwaZulu-Natal, Durban 4000, South Africa.
J Vet Med. 2014;2014:531952. doi: 10.1155/2014/531952. Epub 2014 Sep 11.
Antibiotic resistance in bacteria is affected by the type of antibiotics used and how they are handled. The types of antibiotics used by 110 pig farms in the Ashanti region and the handling practices of the farmers during disease management were assessed. Injectable tetracycline, sulphadimidine, benzylpenicillin, and dihydrostreptomycin containing antibiotics were overly used by the farmers especially in the management of diarrhea, rashes, and coughs. Unsafe storage and disposal practices observed among the farms reflected the abysmal knowledge on appropriate use of antibiotics. Misdiagnosis and inadequate protection during antibiotic handling in the farms increased the risk of antibiotic resistance development and spread. The factors affecting antibiotic resistance development and spread are rife in pig farms in Ashanti region and appropriate education and veterinary interventions are needed to prevent resistant bacteria from becoming endemic in pork and pig farm communities.
细菌中的抗生素耐药性受所用抗生素类型及其处理方式的影响。对阿散蒂地区110个养猪场使用的抗生素类型以及农民在疾病管理期间的处理做法进行了评估。农民过度使用了含注射用四环素、磺胺二甲嘧啶、苄青霉素和二氢链霉素的抗生素，尤其是在腹泻、皮疹和咳嗽的管理中。在这些农场中观察到的不安全储存和处置做法反映出他们在抗生素合理使用方面的知识极度匮乏。农场中抗生素处理期间的误诊和防护不足增加了抗生素耐药性产生和传播的风险。影响抗生素耐药性产生和传播的因素在阿散蒂地区的养猪场中很普遍，需要进行适当的教育和兽医干预，以防止耐药细菌在猪肉和养猪场社区中成为地方病。
