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聚茴香脑磺酸钠对脑膜炎奈瑟菌生长的体外抑制作用。

Inhibitory effect in vitro of sodium polyanethol sulfonate on the growth of Neisseria meningitidis.

作者信息

Eng J, Iveland H

出版信息

J Clin Microbiol. 1975 May;1(5):444-7. doi: 10.1128/jcm.1.5.444-447.1975.

Abstract

The influence of 0.05% sodium polyanethol sulfonate on the growth of 24 strains of Neisseria meningitidis in broth medium was examined; several of the strains were markedly inhibited. A paper disk method was evolved for screening the sensitivity of various bacteria to sodium polyanethol sulfonate on solid medium; the highest sensitivity was observed in N. meningitidis and Neisseria gonorrhoeae. Zones of growth inhibition were also observed in a proportion of strains in certain species of gram-positive cocci, whereas all gram-negative bacilli were uniformly resistant. The implications of these observations for the routine use of sodium polyanethol sulfonate in blood culture media are discussed.

摘要

研究了0.05%的聚茴香脑磺酸钠对24株脑膜炎奈瑟菌在肉汤培养基中生长的影响;其中几株菌受到明显抑制。开发了一种纸片法来筛选各种细菌在固体培养基上对聚茴香脑磺酸钠的敏感性;在脑膜炎奈瑟菌和淋病奈瑟菌中观察到最高敏感性。在一定比例的革兰氏阳性球菌某些菌种中也观察到生长抑制圈,而所有革兰氏阴性杆菌均表现出一致的抗性。讨论了这些观察结果对在血培养培养基中常规使用聚茴香脑磺酸钠的意义。

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Effect of sodium polyanethol sulfonate in blood cultures.聚茴香脑磺酸钠在血培养中的作用。
J Clin Microbiol. 1975 Feb;1(2):119-23. doi: 10.1128/jcm.1.2.119-123.1975.
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Inhibition of Neisseria meningitidis by alpha-amylase.α-淀粉酶对脑膜炎奈瑟菌的抑制作用。
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