Eng J, Iveland H
J Clin Microbiol. 1975 May;1(5):444-7. doi: 10.1128/jcm.1.5.444-447.1975.
The influence of 0.05% sodium polyanethol sulfonate on the growth of 24 strains of Neisseria meningitidis in broth medium was examined; several of the strains were markedly inhibited. A paper disk method was evolved for screening the sensitivity of various bacteria to sodium polyanethol sulfonate on solid medium; the highest sensitivity was observed in N. meningitidis and Neisseria gonorrhoeae. Zones of growth inhibition were also observed in a proportion of strains in certain species of gram-positive cocci, whereas all gram-negative bacilli were uniformly resistant. The implications of these observations for the routine use of sodium polyanethol sulfonate in blood culture media are discussed.
研究了0.05%的聚茴香脑磺酸钠对24株脑膜炎奈瑟菌在肉汤培养基中生长的影响;其中几株菌受到明显抑制。开发了一种纸片法来筛选各种细菌在固体培养基上对聚茴香脑磺酸钠的敏感性;在脑膜炎奈瑟菌和淋病奈瑟菌中观察到最高敏感性。在一定比例的革兰氏阳性球菌某些菌种中也观察到生长抑制圈,而所有革兰氏阴性杆菌均表现出一致的抗性。讨论了这些观察结果对在血培养培养基中常规使用聚茴香脑磺酸钠的意义。