Scribner R K, Welch D F
J Clin Microbiol. 1984 Jul;20(1):40-2. doi: 10.1128/jcm.20.1.40-42.1984.
The inhibitory and bactericidal effects of sodium polyanetholesulfonate on Neisseria meningitidis were neutralized by blood lysis which occurs within the pediatric Isolator 1.5 Microbial tube (E. I. du Pont de Nemours & Co., Inc., Wilmington, Del.). Lysed blood was more effective than 2.5% gelatin in preventing the inhibitory effect. All but 1 of 16 N. meningitidis strains were killed by 0.06% sodium polyanetholesulfonate in the absence of lysed blood, whereas none were killed by 1.0% sodium polyanetholesulfonate when lysed blood was present. The possible clinical relevance of these results was reflected in the improved detection of meningococcemia in children when the Isolator 1.5 Microbial tube was compared with a conventional broth system.
聚茴香脑磺酸钠对脑膜炎奈瑟菌的抑制和杀菌作用被小儿隔离器1.5微生物管（E.I.杜邦公司，特拉华州威尔明顿）内发生的血液溶解所中和。溶血在防止抑制作用方面比2.5%明胶更有效。在没有溶血的情况下，16株脑膜炎奈瑟菌中有15株被0.06%的聚茴香脑磺酸钠杀死，而当有溶血存在时，1.0%的聚茴香脑磺酸钠没有杀死任何菌株。当将隔离器1.5微生物管与传统肉汤系统进行比较时，这些结果在儿童脑膜炎球菌血症检测的改善中得到了体现，反映了这些结果可能具有的临床相关性。
