Walford G A, Nelson W M, McCluskey D R
Department of Child and Adolescent Psychiatry, Royal Belfast Hospital for Sick Children, Northern Ireland.
Arch Dis Child. 1993 Mar;68(3):384-8. doi: 10.1136/adc.68.3.384.
The aims of this study were to determine the characteristics and perceived levels of fatigue and the prevalence of depression in children with chronic fatigue syndrome and to assess the effects of illness on schooling and social functioning. Twelve children with chronic fatigue syndrome were compared with a matched group of children with cystic fibrosis and matched healthy controls. Levels of fatigue (fatigue questionnaire), depression (children's depression inventory), and social adjustment (semistructured interview with parents) were compared between groups. Children with chronic fatigue syndrome had significantly higher median scores for physical and mental fatigue and depressive symptomatology than either comparison group and five children scored as depressed on the children's depression inventory. Schooling and social functioning were seriously disrupted. Children with chronic fatigue syndrome reported high levels of fatigue affecting both physical and mental functioning, the association with depression found in adult studies was confirmed, and social adjustment was poor.
本研究的目的是确定慢性疲劳综合征患儿的疲劳特征、感知水平以及抑郁症患病率，并评估疾病对学业和社交功能的影响。将12名慢性疲劳综合征患儿与一组匹配的囊性纤维化患儿及匹配的健康对照儿童进行比较。比较了各组之间的疲劳水平（疲劳问卷）、抑郁程度（儿童抑郁量表）和社会适应情况（与家长进行半结构化访谈）。慢性疲劳综合征患儿在身体和精神疲劳以及抑郁症状方面的中位数得分显著高于两个对照组，并且有5名儿童在儿童抑郁量表上被评定为抑郁。学业和社交功能受到严重干扰。慢性疲劳综合征患儿报告称高水平的疲劳影响了身体和心理功能，证实了在成人研究中发现的与抑郁症的关联，并且社会适应能力较差。
