肌痛性脑脊髓炎——一种持续性肠道病毒感染？
Myalgic encephalomyelitis--a persistent enteroviral infection?
作者信息
Dowsett E G, Ramsay A M, McCartney R A, Bell E J
机构信息
Basildon Hospital, Essex, UK.
出版信息
Postgrad Med J. 1990 Jul;66(777):526-30. doi: 10.1136/pgmj.66.777.526.
Abstract
Myalgic encephalomyelitis is a common disability but frequently misinterpreted. Amongst 6,000 patients referred for general microbiological diagnosis between 1975 and 1987, 420 cases were recognized. Coxsackie B neutralization tests, in 205 of these, demonstrated significant titres in 103/205 (50%), while of 124 additionally investigated for enteroviral IgM, 38/124 (31%) were positive. This illness is distinguished from a variety of other post-viral states by an unique clinical and epidemiological pattern characteristic of enteroviral infection. Prompt recognition and advice to avoid over-exertion is mandatory. Routine diagnosis, specific therapy and prevention, await further technical advances.
摘要
肌痛性脑脊髓炎是一种常见的致残疾病，但常常被误解。在1975年至1987年间因一般微生物学诊断而转诊的6000名患者中，确诊了420例。其中205例进行了柯萨奇B病毒中和试验，103/205（50%）显示出显著滴度，而在另外124例接受肠道病毒IgM检测的患者中，38/124（31%）呈阳性。这种疾病通过肠道病毒感染特有的独特临床和流行病学模式与其他各种病毒感染后状态相区别。必须迅速识别并建议避免过度劳累。常规诊断、特异性治疗和预防措施，还有待进一步的技术进步。
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